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Small Molecule Mediated Proliferation of Primary Retinal Pigment Epithelial Cells

✍ Scribed by Swoboda, Jonathan G.; Elliott, Jimmy; Deshmukh, Vishal; de Lichtervelde, Lorenzo; Shen, Weijun; Tremblay, Matthew S.; Peters, Eric C.; Cho, Charles Y.; Lu, Bin; Girman, Sergej; Wang, Shaomei; Schultz, Peter G.

Book ID
120307273
Publisher
American Chemical Society
Year
2013
Tongue
English
Weight
306 KB
Volume
8
Category
Article
ISSN
1554-8929

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## Abstract In this work, we have evaluated the effect of the new discovered peptide obestatin on cell proliferation in primary cultures of human retinal epithelial cells (hRPE cells). The results showed that this peptide induced, in a dose‐dependent manner, cell proliferation by MEK/ERK 1/2 phosph