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Ascorbic acid reversibly inhibits proliferation of retinal pigment epithelial cells

✍ Scribed by Heckelen, A. ;Hermel, M. ;Kondring, B. ;Schrage, N. F.

Book ID
109339898
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
663 KB
Volume
82
Category
Article
ISSN
1395-3907

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## Abstract In this work, we have evaluated the effect of the new discovered peptide obestatin on cell proliferation in primary cultures of human retinal epithelial cells (hRPE cells). The results showed that this peptide induced, in a dose‐dependent manner, cell proliferation by MEK/ERK 1/2 phosph