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Small CD4+8+TCRlow thymocytes contain precursors of mature T cells

โœ Scribed by Wojciech Swat; Harald Von Boehmer; Pawel Kisielow

Book ID
102162497
Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
335 KB
Volume
24
Category
Article
ISSN
0014-2980

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Ontogeny of T cell maturation in LEC mut
Ontogeny of T cell maturation in LEC mutant rats which bear a congenital arrest of maturation from CD4+CD8+ to CD4+CD8โˆ’ thymocytes
โœ Takashi Agui; Tohru Sakai; Kozo Matsumoto ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 421 KB ๐Ÿ‘ 1 views

## Abstract LEC rats bear a congenital deficiency in CD4^+^CD8^โˆ’^ thymocytes and peripheral CD4^+^ T cells, and consequently a deficiency in T~h~ cell functions. Ontogeny of T cell maturation in normal and LEC mutant rats was, therefore, investigated. Prenatal development of thymocytes in normal ra