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Interleukin-4 downregulates CD127 expression and activity on human thymocytes and mature CD8+ T cells

✍ Scribed by Angela M. Crawley; Agatha Vranjkovic; Charlene Young; Jonathan B. Angel


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
531 KB
Volume
40
Category
Article
ISSN
0014-2980

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The cutaneous lymphocyte-associated antigen (CLA) represents the homing receptor involved in selective migration of memory/effector T cells to the skin. Numerous reports demonstrated distinct CLA expression on Th1 cells. However, T cells isolated from skin lesions and CLA + T cells circulating in pe