𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Small bowel motility assessment with magnetic resonance imaging

✍ Scribed by Johannes M. Froehlich; Michael A. Patak; Constantin von Weymarn; Christoph F. Juli; Christoph L. Zollikofer; Klaus-Ulrich Wentz

Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
222 KB
Volume
21
Category
Article
ISSN
1053-1807

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Purpose

To assess primarily the feasibility of magnetic resonance imaging (MRI) as a tool to monitor small bowel peristaltic motion and secondarily to validate this technique by demonstrating drug‐induced motility changes.

Materials and Methods

After a standardized oral preparation of Ispaghula husk (Metamucil®) and meglumine gadoterate (Gd‐DOTA; Dotarem®), 10 volunteers underwent dynamic MRI using a two‐dimensional turbofast field echo (TFE) sequence with a slice repetition time of 500 msec. Intraluminal cross‐sectional caliber changes over time were assessed allowing quantification of the peristaltic frequencies and amplitudes of the small gut on various regions of interest. Pharmacologically induced alterations of the peristaltic motion after spasmolytics and gastrokinetic motion enhancers were investigated.

Results

Small bowel diameter measurement resulted in a peristalsis of 10.96 (SD = ±2.51) waves per minute, oscillating regularly with mean amplitudes of 6.65 mm (SD = ±1.15 mm). Peristaltic frequency in normal individuals is consistent with that observed with other techniques. Intravenous administration of scopolamine butylbromide (= hyoscine butylbromide/Buscopan®) resulted in small bowel paralysis within 21.3 seconds (SD = ±2.8 seconds). Prokinetic effect of intravenous metoclopramide (Paspertin®) after Buscopan paralysis was tested in one volunteer, characterized by a slow recovery of peristalsis, which propagated from the proximal to the distal segments and enhanced contraction amplitudes.

Conclusion

Dynamic MRI allows observing and quantifying small bowel peristalsis, characterizing motion patterns, and monitoring the effects of interfering factors such as drugs. J. Magn. Reson. Imaging 2005;21:370–375. © 2005 Wiley‐Liss, Inc.

📜 SIMILAR VOLUMES

Small animal imaging with a clinical mag
Small animal imaging with a clinical magnetic resonance imager
✍ R. Mark Henkelman; John G. van Heteren; Michael J. Bronskill 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 English ⚖ 377 KB 👁 1 views

Any clinical whole-body MR imager can be adapted for experimental small animal imaging. The design of an rf receiver coil and an efficient magnified imaging technique are presented. Application of this small animal imaging technique is illustrated using a study of paramagnetic contrast enhancement o

Quantitative assessment of liver fat wit
Quantitative assessment of liver fat with magnetic resonance imaging and spectroscopy
✍ Scott B. Reeder; Irene Cruite; Gavin Hamilton; Claude B. Sirlin 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 484 KB 👁 1 views

## Abstract Hepatic steatosis is characterized by abnormal and excessive accumulation of lipids within hepatocytes. It is an important feature of diffuse liver disease, and the histological hallmark of nonalcoholic fatty liver disease (NAFLD). Other conditions associated with steatosis include alco

Assessment of small bowel motility funct
Assessment of small bowel motility function With cine-MRI using balanced steady-state free precession sequence
✍ Makoto Wakamiya; Akira Furukawa; Shuzo Kanasaki; Kiyoshi Murata 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 214 KB 👁 1 views

## Abstract ## Purpose: To evaluate the use of cine‐magnetic resonance imaging (MRI) with a steady‐state free precession sequence to monitor and assess small bowel motility. ## Materials and Methods: Sequential MRI, using a balanced steady‐state free precession sequence, was performed in eight h

Automatic quality assessment in structur
Automatic quality assessment in structural brain magnetic resonance imaging
✍ Bénédicte Mortamet; Matt A. Bernstein; Clifford R. Jack Jr.; Jeffrey L. Gunter; 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 434 KB 👁 1 views

## Abstract MRI has evolved into an important diagnostic technique in medical imaging. However, reliability of the derived diagnosis can be degraded by artifacts, which challenge both radiologists and automatic computer‐aided diagnosis. This work proposes a fully‐automatic method for measuring imag

Magnetic resonance imaging with composit
Magnetic resonance imaging with composite (dual) gradients
✍ Dennis L. Parker; K. Craig Goodrich; J. Rock Hadley; Seong-Eun Kim; Sung M. Moon 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 159 KB 👁 1 views

## Abstract The tradeoff between gradient performance factors, size of the imaging region, and physiological factors such as nerve stimulation typically leads to compromises in gradient design and ultimately suboptimal imaging performance. Local gradient systems can add some performance flexibility