## Abstract To explore the relative impact of genetic and nongenetics factors on human brain anatomy during childhood and adolescence development, a collaborative team from the Child Psychiatry Branch of the National Institute of Mental Health and Virginia Commonwealth University is applying struct
Automatic quality assessment in structural brain magnetic resonance imaging
✍ Scribed by Bénédicte Mortamet; Matt A. Bernstein; Clifford R. Jack Jr.; Jeffrey L. Gunter; Chadwick Ward; Paula J. Britson; Reto Meuli; Jean-Philippe Thiran; Gunnar Krueger
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 434 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0740-3194
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
MRI has evolved into an important diagnostic technique in medical imaging. However, reliability of the derived diagnosis can be degraded by artifacts, which challenge both radiologists and automatic computer‐aided diagnosis. This work proposes a fully‐automatic method for measuring image quality of three‐dimensional (3D) structural MRI. Quality measures are derived by analyzing the air background of magnitude images and are capable of detecting image degradation from several sources, including bulk motion, residual magnetization from incomplete spoiling, blurring, and ghosting. The method has been validated on 749 3D T~1~‐weighted 1.5T and 3T head scans acquired at 36 Alzheimer's Disease Neuroimaging Initiative (ADNI) study sites operating with various software and hardware combinations. Results are compared against qualitative grades assigned by the ADNI quality control center (taken as the reference standard). The derived quality indices are independent of the MRI system used and agree with the reference standard quality ratings with high sensitivity and specificity (>85%). The proposed procedures for quality assessment could be of great value for both research and routine clinical imaging. It could greatly improve workflow through its ability to rule out the need for a repeat scan while the patient is still in the magnet bore. Magn Reson Med, 2009. © 2009 Wiley‐Liss, Inc.
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