## Abstract Chromosomal region 18q21 is frequently deleted in colorectal cancer (CRC) and is associated with poor prognosis. Potential tumor suppressor mechanisms altered by 18q21 deletion include mediation of TGFΞ² signaling by SMADs. Following the definition of __SMAD4__ deletion as a negative pre
β¦ LIBER β¦
SMAD4 is a predictive marker for 5-fluorouracil-based chemotherapy in patients with colorectal cancer
β Scribed by Boulay, J-L; Mild, G; Lowy, A; Reuter, J; Lagrange, M; Terracciano, L; Laffer, U; Herrmann, R; Rochlitz, C
- Book ID
- 109997350
- Publisher
- Nature Publishing Group
- Year
- 2002
- Tongue
- English
- Weight
- 112 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0007-0920
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