Members of the transforming growth factor‐β (TGF‐β) superfamily bind to two different serine/threonine kinase receptors, i.e. type I and type II receptors. Upon ligand binding, type I receptors specifically activate intracellular Smad proteins. R‐Smads are direct substrates of type I receptors; Smad
✦ LIBER ✦
Smad-dependent and Smad-independent pathways in TGF-β family signalling
✍ Scribed by Derynck, Rik; Zhang, Ying E.
- Book ID
- 109891423
- Publisher
- Nature Publishing Group
- Year
- 2003
- Tongue
- English
- Weight
- 558 KB
- Volume
- 425
- Category
- Article
- ISSN
- 0028-0836
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Two major Smad pathways in TGF-β superfa
✍
Keiji Miyazawa; Masahiko Shinozaki; Takane Hara; Toshio Furuya; Kohei Miyazono
📂
Article
📅
2002
🏛
John Wiley and Sons
🌐
English
⚖ 495 KB
Non-Smad pathways in TGF-β signaling
✍
Zhang, Ying E
📂
Article
📅
2008
🏛
Nature Publishing Group
🌐
English
⚖ 884 KB
TGF-β and smad signalling in fibrosis
✍
David J Abraham
📂
Article
📅
2008
🏛
John Wiley and Sons
🌐
English
⚖ 68 KB
Differential regulation of TGF-β signali
✍
Kretschmer, Anny; Moepert, Kristin; Dames, Sibylle; Sternberger, Maria; Kaufmann
📂
Article
📅
2003
🏛
Nature Publishing Group
🌐
English
⚖ 565 KB
Role of Smads in TGFβ signaling
✍
Carl-Henrik Heldin; Aristidis Moustakas
📂
Article
📅
2011
🏛
Springer-Verlag
🌐
English
⚖ 423 KB
TGF-β signaling, Smads, and tumor suppre
✍
Richard W. Padgett; Pradeep Das; Srikant Krishna
📂
Article
📅
1998
🏛
John Wiley and Sons
🌐
English
⚖ 262 KB
The transforming growth factor- (TGF-) superfamily is used throughout animal development for regulating the growth and patterning of many tissue types. During the past few years, rapid progress has been made in deciphering how TGF- signals are transduced from outside the cell to the nucleus. This