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Slow-Release Human Recombinant Bone Morphogenetic Protein-2 Embedded Within Electrospun Scaffolds for Regeneration of Bone Defect: In Vitro and In Vivo Evaluation

✍ Scribed by Srouji, Samer; Ben-David, Dror; Lotan, Rona; Livne, Erella; Avrahami, Ron; Zussman, Eyal


Book ID
120989385
Publisher
Mary Ann Liebert
Year
2011
Tongue
English
Weight
676 KB
Volume
17
Category
Article
ISSN
1937-3341

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## Abstract Bone morphogenetic protein‐2 (BMP‐2) plays a key role in osteogenesis. Biomaterials used for the sustained delivery of BMP‐2 __in vivo__ have shown therapeutic benefits. In the present study, BMP‐2 was loaded in porous silk fibroin scaffolds derived from silkworm cocoons (2.4 Β± 0.14 ΞΌg