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Skin permeability of various drugs with different lipophilicity

โœ Scribed by Cheon Koo Lee; Takahiro Uchida; Kazuhisa Kitagawa; Akira Yagi; Nak-Seo Kim; Shigeru Goto

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
492 KB
Volume
83
Category
Article
ISSN
0022-3549

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๐Ÿ“œ SIMILAR VOLUMES

Effect of barrier disruption by acetone
Effect of barrier disruption by acetone treatment on the permeability of compounds with various lipophilicities: Implications for the permeability of compromised skin
โœ Jui-Chen Tsai; Hamm-Ming Sheu; Pi-Lien Hung; Ching-Ling Cheng ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 355 KB

The permeability of compromised skin barrier was investigated in vitro using acetone-disrupted hairless mouse skin as a model membrane. The effect of compound lipophilicity was studied using sucrose, caffeine, hydrocortisone, estradiol, and progesterone as model compounds. The results demonstrated t