In previous studies (Yoneto et al., 1995. J Pharm Sci 84:312-317; Kim et al., 1992. Int J Pharm 80:17-31; and Warner et al., 2001. J Pharm Sci 90:1143-53), the transport enhancing effects of four homologous series of enhancers-the n-alkanols, 1-alkyl-2-pyrrolidones, 1,2-alkanediols, and N,N-dimethyl
β¦ LIBER β¦
Mechanistic study of chemical skin permeation enhancers with different polar and lipophilic functional groups
β Scribed by Ning He; Kevin S. Warner; Doungdaw Chantasart; Dalia S. Shaker; William I. Higuchi; S. Kevin Li
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 234 KB
- Volume
- 93
- Category
- Article
- ISSN
- 0022-3549
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Previous investigations in our laboratory on the inΒ―uence of the n-alkanols and the 1-alkyl-2-pyrrolidones as skin permeation enhancers for steroid molecules as permeants demonstrated that the enhancer potencies (based on aqueous concentration values) of these two homologous series were the same whe