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Skin necrosis and protein C deficiency associated with vitamin K depletion in a patient with renal failure

✍ Scribed by Ramesh Soundararajan; David J. Leehey; Alex W. Yu; Todd S. Ing; J.Bruce Miller

Book ID
115684064
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
809 KB
Volume
93
Category
Article
ISSN
1555-7162

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Skin necrosis is a rare but debilitating complication of treatment with vitamin K antagonist anticoagulants such as warfarin. A clinically similar syndrome has been reported less frequently with heparin therapy. We recently managed a thirty-year-old female patient who developed skin necrosis on her