✦ LIBER ✦

Skin melanoma of the head and neck: Prognostic factors and recurrence-free survival in 512 patients

✍ Scribed by Anders P. Andersson; Jorgen Gottlieb; Krzysztof T. Drzewiecki; Klaus Hou-Jensen; Knud Sondergaard

Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 374 KB
Volume: 69
Category: Article
ISSN: 0008-543X
DOI: 10.1002/cncr.2820690515

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The clinicopathologic and therapeutic data of 512 patients, with clinical Stage I invasive head and neck melanoma of the skin were retrospectively evaluated. There were 287 females and 225 males. Median age at primary‐surgery was 65 years (range, 18 to 96 years). Median observation period was 5 years (range, 1 month to 25 years). Site of first recurrence was local in 7% (38 of 512), regional in 13% (67 of 512) and distant in 6% (31 of 512). Sex, age, ulcerated tumor, and tumor thickness were found to act as independent risk factors to recurrence‐free survival by Cox multivariate regression analysis. In addition, size of excision margin was found to be of no significance to survival without relapse when adjusting for the independent risk factors.

📜 SIMILAR VOLUMES

Sentinel node biopsy in patients with cu

Sentinel node biopsy in patients with cutaneous melanoma of the head and neck: Recurrence and survival study

✍ Fernando Gomez-Rivera; Alfredo Santillan; Andrea Barber McMurphey; George Parask 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 154 KB

## Abstract ## Background. Controversy remains regarding the benefits of sentinel lymph node (SLN) biopsy for predicting survival in cutaneous melanoma of the head and neck (CMHN). ## Methods. We analyzed the factors associated with the recurrence and survival of CMHN patients treated in our ins

Recurrence at the primary site in head a

Recurrence at the primary site in head and neck cancer and the significance of neck lymph node metastases as a prognostic factor

✍ Charles R. Leemans; Rammohan Tiwari; Jos J. P. Nauta; Isaac Van Der Waal; Gordon 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 347 KB 👁 2 views

Background. Biologic aggressiveness of head and neck carcinoma is reflected in its capability to metastasize to regional lymph nodes and its propensity to recur after treatment. Methods. The authors report on 244 patients treated at the Department of Otolaryngology-Head and Neck Surgery of the Free

Factors affecting long-term survival in

Factors affecting long-term survival in patients with recurrent head and neck cancer may help define the role of post-treatment surveillance

✍ Amit Agrawal; Thomas H. Hammond; Gregory S. Young; Amanda L. Avon; Enver Ozer; D 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 211 KB

## Abstract ## Objectives/Hypothesis: Assess impact of clinical variables upon survival in patients diagnosed with recurrent head and neck carcinoma and better delineate role of post‐treatment surveillance. ## Methods: Variables including previous tumor site, stage, prior therapy, location of re

An analysis of skin tests and their rela

An analysis of skin tests and their relationship to recurrence and survival in stage III and stage IV melanoma patients

✍ Elisa T. Lee; D. Richard Ishmael; Richard H. Bottomley; J. Lee Murray 📂 Article 📅 1982 🏛 John Wiley and Sons 🌐 English ⚖ 438 KB 👁 1 views

Towards further understanding of prognos

Towards further understanding of prognostic factors for head and neck cancer patients: The example of hypopharyngeal cancer

✍ Stephen F. Hall; Patti A. Groome; Jonathan Irish; Brian O'Sullivan 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 397 KB

## Abstract ## Objectives: Knowledge of prognostic factors is essential for patient care and research. The objectives of this study were to demonstrate that prognostic factors and their impact can vary depending on study design and to examine the relationships between select prognostic factors. #

Assessment of lymphatic drainage pattern

Assessment of lymphatic drainage patterns and implications for the extent of neck dissection in head and neck melanoma patients

✍ W. Martin C. Klop; Hidde J. Veenstra; Lenka Vermeeren; Omgo E. Nieweg; Alfons J. 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 128 KB

## Abstract ## Background and Objectives The aim of this study is to evaluate lymphatic drainage with sentinel node location data in patients with head and neck cutaneous melanoma, and to determine the implications for the extent of therapeutic neck dissections. ## Methods Sixty‐five patients wi