Skin basement membrane immunofluorescence in rheumatoid arthritis
β Scribed by Daniel C. Deboer; Roland W. Moskowitz; Beno Michel
- Publisher
- John Wiley and Sons
- Year
- 1977
- Tongue
- English
- Weight
- 300 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0004-3591
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Synovial membrane biopsy specimens from 15 rheumatoid arthritis patients were examined using routine histologic stains and monoclonal antibodies directed against cell surface antigens. Three patterns of lymphoid cell infiltrates were recognized: 1) diffuse infiltration of T cells that surrounded clu
Objective. To determine methotrexate (MTX) concentrations in the synovial membrane (SM) and cortical and trabecular bone of rheumatoid arthritis (RA) patients. Methods. Ten RA patients (9 women, 1 man; mean +. SD age 49.2 f 10.6, mean disease duration 13.2 f 9.9 years) undergoing surgical procedures