Skin allografts in the newt,Notopthalmus viridescens: Cessation of blood flow as an indicator of rejection,

✍ Scribed by Hightower, James A. ;St. Pierre, Ronald L.

• Publisher: John Wiley and Sons
• Year: 1972
• Tongue: English
• Weight: 871 KB
• Volume: 181
• Category: Article
• ISSN: 0022-104X
• DOI: 10.1002/jez.1401810305

✦ Synopsis

Abstract

Histological sections and surface views of skin allografts from newts were examined. It was determined that complete cessation of blood flow through the allografts was a valid indicator of graft rejection.

The following sequence of events was detected within allografts as they were rejected; (1) primary vasodilation 8.4 ± 3.6 days after grafting; (2) re‐establishment of circulation at days 11.3 ± 3.5 after grafting; (3) signs of rejection (viz., secondary vasodilation, stasis and hemorrhage) at days 20.9 ± 5.0 after grafting, and (4) complete rejection at days 36.1 ± 7.0. There was no evidence of sexual dimorphism in any of the newts examined with regard to skin allograft rejection.