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Skeletal muscle in paramyotonia congenita: biochemistry, histochemistry and morphology

✍ Scribed by Mogens Laue Friis; Torsten Johnsen; Bengt Saltin; Olaf B. Paulson

Book ID
114782102
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
712 KB
Volume
71
Category
Article
ISSN
0001-6314

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πŸ“œ SIMILAR VOLUMES

Paramyotonia congenita: The R1448P Na+ c
Paramyotonia congenita: The R1448P Na+ channel mutation in adult human skeletal muscle
✍ Dr H. Lerche; Dr N. Mitrovic; V. Dubowitz; Dr F. Lehmann-Horn πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 866 KB

Twitch force and Na' currents were investigated in a muscle biopsy specimen from a patient with paramyotonia congenita carrying the dominant Arg-1448-Pro mutation in the skeletal muscle sodium channel. Cooling of the muscle fibers caused sustained membrane depolarization that resulted in reduced twi