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SIVMAC Vpx improves the transduction of dendritic cells with nonintegrative HIV-1-derived vectors

✍ Scribed by Berger, G; Goujon, C; Darlix, J-L; Cimarelli, A

Book ID
109855066
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
186 KB
Volume
16
Category
Article
ISSN
0969-7128

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## Abstract ## Background HIV‐1 fails to successfully infect mouse T cells as a result of several blocks in the viral replication cycle. We investigated whether this also impacted on the use of HIV‐1 derived lentiviral vectors for stable gene transfer into mouse T cells. ## Methods Freshly isola