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Site-Specific Introduction of Sialic Acid into Insulin

✍ Scribed by Masaaki Sato; Reiko Sadamoto; Kenichi Niikura; Kenji Monde; Hirosato Kondo; Shin-Ichiro Nishimura


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
223 KB
Volume
43
Category
Article
ISSN
0044-8249

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## Abstract The __Hammett__ approach, as a new deductive tool, was introduced to characterize the otherwise inaccessible minor protonation pathway of tenoxicam (**1**), the non‐steroidal anti‐inflammatory drug. A total of eight compounds, constituting a systematic series of side chain‐substituted a