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Site-Specific DNA-Controlled Fusion of Single Lipid Vesicles to Supported Lipid Bilayers

✍ Scribed by Simonsson, Lisa V.; Jönsson, Peter; Stengel, Gudrun; Höök, Fredrik

Book ID
122223083
Publisher
Biophysical Society
Year
2010
Tongue
English
Weight
53 KB
Volume
98
Category
Article
ISSN
0006-3495

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Site-Specific DNA-Controlled Fusion of S
Site-Specific DNA-Controlled Fusion of Single Lipid Vesicles to Supported Lipid Bilayers
✍ Lisa Simonsson; Peter Jönsson; Gudrun Stengel; Fredrik Höök 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 558 KB

## Abstract __We investigate the Ca^2+^‐triggered fusion of lipid vesicles site‐selectively tethered to a DNA‐modified supported lipid bilayer array, with the DNA strands designed such that hybridization occurs in a zipperlike fashion. Prior to the addition of Ca^2+^, which is observed to induce do

Inside Cover: Site-Specific DNA-Controll
Inside Cover: Site-Specific DNA-Controlled Fusion of Single Lipid Vesicles to Supported Lipid Bilayers (ChemPhysChem 5/2010)
✍ Lisa Simonsson; Peter Jönsson; Gudrun Stengel; Fredrik Höök 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 638 KB

Site-specific DNA-programmed single-vesicle fusion to a supported lipid bilayer is demonstrated by F. Hççk et al. on p. 1011. Cholesterol-modified DNA zippers are used to constitute a reduced model system of the SNARE-protein complex controlling synaptic vesicle fusion.