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Sister chromatid exchanges induced by mutagenic carcinogens in normal and xeroderma pigmentosum cells

✍ Scribed by WOLFF, SHELDON; RODIN, B.; CLEAVER, J. E.

Book ID
109703667
Publisher
Nature Publishing Group
Year
1977
Tongue
English
Weight
349 KB
Volume
265
Category
Article
ISSN
0028-0836

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UV-light induced sister chromatid exchan
UV-light induced sister chromatid exchanges in xeroderma pigmentosum lymphocytes
✍ A. Dorothee SchΓΆnwald; E. Passarge πŸ“‚ Article πŸ“… 1977 πŸ› Springer 🌐 English βš– 264 KB

Cultured lymphocytes from 9 patients with clinically different types of xeroderma pigmentosum were exposed to ultraviolet light at 24 h. An increased rate of sister chromatid exchanges were observed in 6 patients (128--148% increase in three, 34--51% in three), but not in three patients with deSanct