## Abstract Chemical transformation of cultured human skin fibroblasts (PF) derived from individuals with hereditary adenomatosis of the colon and rectum is reported. Cells treated only with various levels of N‐methyl‐N′‐nitro‐N‐nitrosoguanidine (MNNG) underwent morphological alteration. The morpho
Sister chromatid exchange with and without in vitro mutagen induction in cultured skin fibroblasts from patients with adenomatosis of the colon and rectum
✍ Scribed by Sverre Heim
- Book ID
- 115089160
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 508 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0009-9163
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract A heritable propensity to develop malignant lesions is found in individuals with familial adenomatosis of the colon and rectum (ACR) and the Gardner's syndrome variant, an autosomal dominant trait. In the present study, the growth characteristics of cultured skin fibroblasts (SF) derive
## Abstract The frequency of sister chromatid exchange (SCE) in WI‐38 cells was estimated by the 5‐bromodeoxyuridine (BrdUrd)‐dye technique after one hour's exposure to cyclophosphamide (CY), N‐methyl‐N′‐nitro‐N‐nitrosoguanidine (MNNG), 4‐nitroquinoline‐1‐oxide (4NQO), and maleic hydrazide (MH) wit
The inducibility of sister chromatid exchanges (SCEs) by benzo(a)pyrene (6P) was studied in cultured peripheral blood lymphocytes of I5 untreated lung cancer patients and 25 healthy persons including I I high-and 14 low-cancer-risk individuals tentatively classified by the familial history of lung c