Sister chromatid exchange and methylazoxymethanol acetate
โ Scribed by L.A. Evans; M. Kevin; E.C. Jenkins
- Book ID
- 119091744
- Publisher
- Elsevier Science
- Year
- 1976
- Tongue
- English
- Weight
- 66 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0165-1161
No coin nor oath required. For personal study only.
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Although baseline levels of SCE appear to be similar in metaphase cells derived from young and old human skin fibroblast cultures, a significant decline in both MMC- and AAAF-induced sister chromatid exchanges was observed in the older cell populations. Considerable variation exists in the levels of
Sister chromatid exchange (SCE) is a genetic indicator of DNA damage in mammalian cells and may afford a sensitive monitor to follow genomic instability of some individuals with fragile chromosomal diseases or malignancies. In studies on the effect of dinitrosopiperazine (DNP), aflatoxin B, (AFB,),