Sister chromatid exchange (SCE) frequencies were studied in peripheral lymphocytes from 16 patients with newly diagnosed acute lymphoblastic leukemia (ALL) prior to the initiation of chemotherapy. The mean SCE frequency (mean +/- SE) for these patients was 12.2 +/- 0.2 per metaphase, which was signi
Sister chromatid exchange analysis in acute leukemia patients
✍ Scribed by Musaffe Tuna; Sevilhan Artan; Sefer Gezer; Bekir Sitki Şayli; Nurettin Başaran
- Book ID
- 113253314
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 272 KB
- Volume
- 79
- Category
- Article
- ISSN
- 0165-4608
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## Abstract Sister chromatid exchange (SCE) frequency has been analysed after short‐term culture of leukemic bone marrow cells of eight untreated patients with acute leukemia. Compared to normal bone marrow, results show a statistically significant decrease of SCE (__p__ < 0.001) in euploid as well
## Abstract The sister chromatid exchange (SCE) frequency in bone‐marrow cells of 12 untreated patients with chronic myelocytic leukemia (CML) was analysed and compared with the SCE frequency in bone‐marrow cells of nine healthy persons. In normal persons the SCE ranged from 3.64 to 5.15 per cell.