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Sirtuin Deacetylases as Therapeutic Targets in the Nervous System

✍ Scribed by Langley, Brett; Sauve, Anthony

Book ID
121613668
Publisher
Springer-Verlag
Year
2013
Tongue
English
Weight
421 KB
Volume
10
Category
Article
ISSN
1933-7213

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Histone deacetylases (HDACs) are enzymes that cleave off acetyl groups from acetyl-lysine residues in histones and various nonhistone proteins. Four different classes of HDACs have been identified in humans so far. Although classes I, II, and IV are zinc-dependent amidohydrolases, class III HDACs de