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Sinusoidal obstruction syndrome: Correct dosing of monocrotaline and the validity of the rat model

โœ Scribed by Tarek Ezzat; Dipok K. Dhar; Steven W.M. Olde Damink

Book ID
115559395
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
51 KB
Volume
107
Category
Article
ISSN
0022-4790

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๐Ÿ“œ SIMILAR VOLUMES

Decreased hepatic nitric oxide productio
Decreased hepatic nitric oxide production contributes to the development of rat sinusoidal obstruction syndrome
โœ Laurie D. Deleve; Xiangdong Wang; Gary C. Kanel; Yoshiya Ito; Nancy W. Bethea; M ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 979 KB

This study examined the role of decreased nitric oxide (NO) in the microcirculatory obstruction of hepatic sinusoidal obstruction syndrome (SOS). SOS was induced in rats with monocrotaline. Monocrotaline caused hepatic vein NO to decrease by 30% at 24 hours and by 70% at 72 hours; this decrease pers