Review article: updates in the pathogenesis and therapy of hepatic sinusoidal obstruction syndrome
β Scribed by A. HELMY
- Book ID
- 108604393
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 158 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0269-2813
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This study examined the role of decreased nitric oxide (NO) in the microcirculatory obstruction of hepatic sinusoidal obstruction syndrome (SOS). SOS was induced in rats with monocrotaline. Monocrotaline caused hepatic vein NO to decrease by 30% at 24 hours and by 70% at 72 hours; this decrease pers
Sinusoidal obstruction syndrome (SOS) is a rare, life-threatening clinical syndrome resulting from sinusoidal congestion, and it is characterized by hepatomegaly, ascites, weight gain, and jaundice. The frequency of this condition after liver transplantation (LT) is low, but when SOS is severe and r