## Abstract Singlet oxygen (^1^O~2~) is the major cytotoxic agent responsible for cell killing for typeβII photodynamic therapy (PDT). An empirical fourβparameter macroscopic model is proposed to calculate the βapparent reacted ^1^O~2~ concentrationβ, [^1^O~2~]~__rx__~, as a clinical PDT dosimetry
Singlet oxygen dosimetry modeling for photodynamic therapy
β Scribed by X. Liang; T. Busch; T.C. Zhu
- Book ID
- 116823237
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 61 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1572-1000
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
A light dosimetry model for photodynamic therapy is described leading to the dependence of necrosis depth on incident light dose. Semiempirical dosimetry relations are derived for four modes of light delivery. Results for PhotofrinB I1 at 630 nm are summarized in graphical form. Numerical values of
Background and Objective: Photodynamic therapy (PDT) based on topical application of photosensitizers has been under development over the last years. Typical applications are treatment of basal cell carcinoma of the skin and photoablation of the endometrium. The dosimetry for topically administered