## Background and objective: Photodynamic therapy (pdt) is an efficient technique to treat superficial early cancers in the pharynx, esophagus, and tracheo-bronchial tree. however, the lack of selectivity of some of the clinically used photosensitizers can result in significant damage to the health
Light dosimetry model for photodynamic therapy treatment planning
β Scribed by Dr. Leonard I. Grossweiner
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 765 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0196-8092
No coin nor oath required. For personal study only.
β¦ Synopsis
A light dosimetry model for photodynamic therapy is described leading to the dependence of necrosis depth on incident light dose. Semiempirical dosimetry relations are derived for four modes of light delivery. Results for PhotofrinB I1 at 630 nm are summarized in graphical form. Numerical values of the parameters and necrosis depth calculations are compared with literature data.
π SIMILAR VOLUMES
Background and Objective: Photodynamic therapy (PDT) based on topical application of photosensitizers has been under development over the last years. Typical applications are treatment of basal cell carcinoma of the skin and photoablation of the endometrium. The dosimetry for topically administered
## Abstract Singlet oxygen (^1^O~2~) is the major cytotoxic agent responsible for cell killing for typeβII photodynamic therapy (PDT). An empirical fourβparameter macroscopic model is proposed to calculate the βapparent reacted ^1^O~2~ concentrationβ, [^1^O~2~]~__rx__~, as a clinical PDT dosimetry
Background. Photodynamic therapy (PDT) is being evaluated for treatment of localized head and neck cancer. ''Light dose'' is usually prescribed as incident fluence, which takes no account of reflected and scattered light. This study investigates variations in total tissue fluence for a given inciden