✦ LIBER ✦

Single-point plasma or urine dextromethorphan method for determining CYP3A activity

✍ Scribed by Benjamin Pei-Chung Kuo; Oliver Yoa-Pu Hu; Cheng-Huei Hsiong; Li-Heng Pao; Ting-Shien Chen; Chi-Feng Hung

Book ID: 101701828
Publisher: John Wiley and Sons
Year: 2003
Tongue: English
Weight: 85 KB
Volume: 24
Category: Article
ISSN: 0142-2782
DOI: 10.1002/bdd.373

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

A Urine Metabolic Ratio of Dextromethorp

A Urine Metabolic Ratio of Dextromethorphan and 3-Methoxymorphinan as a Probe for CYP3A Activity and Prediction of Cyclosporine Clearance in Healthy Volunteers

✍ David I. Min; Yi-Min Ku; Aungkana Vichiendilokkul; Lawrence L. Fleckenstein 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 52 KB

Development and validation of a chemical

Development and validation of a chemical hydrolysis method for dextromethorphan and dextrophan determination in urine samples: Application to the assessment of CYP2D6 activity in fibromyalgia patients

✍ Y. Daali; S. Cherkaoui; F. Doffey-Lazeyras; P. Dayer; J.A. Desmeules 📂 Article 📅 2008 🏛 Elsevier Science 🌐 English ⚖ 882 KB

High-performance liquid chromatographic

High-performance liquid chromatographic method for determination of DN-2327, a novel non-benzodiazepine anxiolytic, and/or its active metabolite in human plasma and urine

✍ Ziad Hussein; Sou-yie Chu; G. Richard Granneman 📂 Article 📅 1993 🏛 Elsevier Science ⚖ 664 KB

A validated SIM GC/MS method for the sim

A validated SIM GC/MS method for the simultaneous determination of dextromethorphan and its metabolites dextrorphan, 3-methoxymorphinan and 3-hydroxymorphinan in biological matrices and its application to in vitro CYP2D6 and CYP3A4 inhibition study

✍ Marios Spanakis; Ioannis S. Vizirianakis; Maria Mironidou-Tzouveleki; Ioannis Ni 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 347 KB 👁 2 views

## Abstract Dextromethorphan is used as a probe drug for assessing CYP2D6 and CYP3A4 activity __in vivo__ and __in vitro__. A SIM GC/MS method without derivatization for the simultaneous determination of dextromethorphan and its metabolites, dextrorphan, 3‐methoxymorphinan and 3‐hydroxymorphinan, i

A liquid chromatography method with sing

A liquid chromatography method with single quadrupole mass spectrometry for quantitative determination of indomethacin in maternal plasma and urine of pregnant patients

✍ Wang, Xiaoming; Vernikovskaya, Daria I.; Nanovskaya, Tatiana N.; Rytting, Erik; 📂 Article 📅 2013 🏛 Elsevier Science 🌐 English ⚖ 286 KB

A rapid, sensitive method for the determ

A rapid, sensitive method for the determination of 3-methylhistidine levels in urine and plasma using high-pressure liquid chromatography

✍ S.J. Wassner; J.L. Schlitzer; J.B. Li 📂 Article 📅 1980 🏛 Elsevier Science 🌐 English ⚖ 433 KB