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Single-nucleotide polymorphisms (SNPs) of the IRF6 and TFAP2A in non-syndromic cleft lip with or without cleft palate (NSCLP) in a northern Chinese population

✍ Scribed by Jinna Shi; Tao Song; Xiaohui Jiao; Chunlin Qin; Jin Zhou

Book ID: 116301916
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 189 KB
Volume: 410
Category: Article
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2011.06.006

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## Abstract ## Objectives/Hypothesis: Interferon regulatory factor 6 (__IRF6__), the gene that causes van der Woude syndrome (VWS), is a candidate gene for nonsyndromic cleft lip with or without cleft palate (NSCLP) because a number of studies have supported an association between NSCLP and single