Association of Single Nucleotide Polymorphisms in IRF6 and TGFA Genes With Nonsyndromic Cleft Lip With Or Without Cleft Palate in Chinese Patients
β Scribed by Ya Shen; Yugui Cui; Weidong Wan; Xiaoping Zhou; Lu Cheng; Zuhong Lu; Jiayin Liu
- Book ID
- 117696632
- Publisher
- Chinese Electronic Periodical Services
- Year
- 2009
- Tongue
- English
- Weight
- 156 KB
- Volume
- 23
- Category
- Article
- ISSN
- 1007-4376
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## Abstract **BACKGROUND:** Nonsyndromic cleft lip with or without cleft palate (NCL/P) is a common structural malformation with a complex and multifactorial etiology. It has been shown that maternal psychological stress in the periconceptional period can contribute to an increase in the risk of NC
## Abstract ## Objectives/Hypothesis: Interferon regulatory factor 6 (__IRF6__), the gene that causes van der Woude syndrome (VWS), is a candidate gene for nonsyndromic cleft lip with or without cleft palate (NSCLP) because a number of studies have supported an association between NSCLP and single