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Single nucleotide polymorphisms in nucleotide excision repair genes, cancer treatment, and head and neck cancer survival

โœ Scribed by Wyss, Annah B.; Weissler, Mark C.; Avery, Christy L.; Herring, Amy H.; Bensen, Jeannette T.; Barnholtz-Sloan, Jill S.; Funkhouser, William K.; Olshan, Andrew F.


Book ID
121534135
Publisher
Springer Netherlands
Year
2014
Tongue
English
Weight
519 KB
Volume
25
Category
Article
ISSN
0957-5243

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## Abstract ## Objectives/Hypothesis: Single nucleotide polymorphisms (SNPs) of certain genes involved in drug metabolism correlate with survival. ## Methods: We evaluated the presence of SNPs in six genes (__CYP2C8__, __GSTT1__, __GSTP1__, __MDR1โ€57__, __MDR1โ€62__, and __ERCC1__) and the respon