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Polymorphisms in base-excision repair and nucleotide-excision repair genes in relation to lung cancer risk

✍ Scribed by Kim De Ruyck; Marcin Szaumkessel; Isabelle De Rudder; Annelore Dehoorne; Anne Vral; Kathleen Claes; Anja Velghe; Jan Van Meerbeeck; Hubert Thierens

Book ID
116759283
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
163 KB
Volume
631
Category
Article
ISSN
1383-5718

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Polymorphisms in the DNA nucleotide exci
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The lung cancer mortality rate in Xuan Wei County is among the highest in China and has been attributed to exposure to indoor smoky coal emissions that contain very high levels of polycyclic aromatic hydrocarbons (PAHs). Nucleotide excision repair (NER) plays a key role in reversing DNA damage from