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Single nucleotide polymorphisms in base-excision repair genes hOGG1, APE1 and XRCC1 do not alter risk of Alzheimer's disease

✍ Scribed by Hande Parıldar-Karpuzoğlu; Semra Doğru-Abbasoğlu; Hasmet A. Hanagasi; Berrin Karadağ; Hakan Gürvit; Murat Emre; Müjdat Uysal


Book ID
116770684
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
151 KB
Volume
442
Category
Article
ISSN
0304-3940

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Genetic polymorphisms in DNA base-excisi
✍ Chunying Li; Zhibin Hu; Jiachun Lu; Zhensheng Liu; Li-E Wang; Adel K. El-Naggar; 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 242 KB 👁 2 views

## Abstract ## BACKGROUND. Tobacco smoke contains numerous carcinogens that cause DNA damage, including oxidative lesions that are removed effectively by the base‐excision repair (BER) pathway, in which adenosine diphosphate ribosyl transferase (ADPRT), x‐ray repair cross‐complementing 1 (XRCC1),