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Polymorphisms of Base-Excision Repair Genes hOGG1 326cys and XRCC1 280His Increase Hepatocellular Carcinoma Risk

✍ Scribed by Tao Yuan, Jingyu Wei, Jie Luo, Menggang Liu, Shaoli Deng, Ping Chen


Book ID
118298792
Publisher
Springer US
Year
2012
Tongue
English
Weight
230 KB
Volume
57
Category
Article
ISSN
0163-2116

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## Abstract ## BACKGROUND. Tobacco smoke contains numerous carcinogens that cause DNA damage, including oxidative lesions that are removed effectively by the base‐excision repair (BER) pathway, in which adenosine diphosphate ribosyl transferase (ADPRT), x‐ray repair cross‐complementing 1 (XRCC1),