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Single nucleotide polymorphisms in ABCC2 and ABCB1 genes and their clinical impact in physiology and drug response

✍ Scribed by Morimasa Wada

Book ID
116333882
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
168 KB
Volume
234
Category
Article
ISSN
0304-3835

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## Abstract The prognosis of lung cancer patients treated with chemotherapy is poor, motivating the search for predictive factors. Single nucleotide polymorphisms (SNPs) in membrane transporter genes could influence the pharmacokinetics of cytostatic drugs and therefore affect treatment outcome. We