A comprehensive study of polymorphisms in the ABCB1, ABCC2, ABCG2, NR1I2 genes and lymphoma risk
✍ Scribed by Daniele Campa; Katja Butterbach; Susan L. Slager; Christine F. Skibola; Silvia de Sanjosé; Yolanda Benavente; Nikolaus Becker; Lenka Foretova; Marc Maynadie; Pierluigi Cocco; Anthony Staines; Rudolf Kaaks; Paolo Boffetta; Paul Brennan; Lucia Conde; Paige M. Bracci; Neil E. Caporaso; Sara S. Strom; Nicola J. Camp; James R. Cerhan; GEC Consortium; Federico Canzian; Alexandra Nieters
- Book ID
- 112101602
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- French
- Weight
- 450 KB
- Volume
- 131
- Category
- Article
- ISSN
- 0020-7136
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## Abstract ## BACKGROUND. The authors investigated whether __ABCB1, ABCC2,__ and __ABCG2__ genetic polymorphisms affect pharmacokinetics (PK) of irinotecan and treatment outcome of patients with advanced nonsmall cell lung cancer (NSCLC). ## METHODS. Blood samples from 107 NSCLC patients treate