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Single nucleotide polymorphisms and risk of recurrence of renal-cell carcinoma: a cohort study

✍ Scribed by Fabio AB Schutz; Mark M Pomerantz; Kathryn P Gray; Michael B Atkins; Jonathan E Rosenberg; Michelle S Hirsch; David F McDermott; Megan E Lampron; Gwo-Shu Mary Lee; Sabina Signoretti; Philip W Kantoff; Matthew L Freedman; Toni K Choueiri

Book ID
118180060
Publisher
The Lancet
Year
2013
Tongue
English
Weight
158 KB
Volume
14
Category
Article
ISSN
1470-2045

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## Abstract The FAS/FAS ligand (FASL) system plays a key role in regulating apoptotic cell death, and corruption of this signaling pathway has been shown to participate in tumorigenesis. However, the effects of functional promoter polymorphisms of the __CASP8__, __FAS__, and __FASL__ genes on risk