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Single-molecule imaging of EGFR signalling on the surface of living cells

✍ Scribed by Yanagida, Toshio; Sako, Yasushi; Minoghchi, Shigeru


Book ID
109767877
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
313 KB
Volume
2
Category
Article
ISSN
1465-7392

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Single-molecule imaging of EGFR signalli
✍ Yanagida, Toshio; Sako, Yasushi; Minoghchi, Shigeru πŸ“‚ Article πŸ“… 2000 πŸ› Nature Publishing Group 🌐 English βš– 313 KB

The early events in signal transduction from the epidermal growth factor (EGF) receptor (EGFR) are dimerization and autophosphorylation of the receptor, induced by binding of EGF. Here we observe these events in living cells by visualizing single molecules of fluorescent-dye-labelled EGF in the plas