Plasma and whole blood concentrations of proguanil, its active metabolite cycloguanil, and the inactive metabolite 4-chlorophenyl-biguanide, were measured by HPLC in 10 healthy Karen women in the last trimester of pregnancy, following a 200 mg single oral dose of proguanil. Four of these women were
Single dose pharmacokinetics of proguanil and its metabolites in pregnancy
โ Scribed by Wangboonskul, J. (author);White, N. J. (author);Nosten, F. (author);ter Kuile, F. (author);Moody, R. R. (author);Taylor, R. B. (author)
- Publisher
- Springer-Verlag
- Year
- 1993
- Tongue
- English
- Weight
- 491 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0031-6970
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