Single dose intravenous thioacetamide administration as a model of acute liver damage in rats
โ Scribed by Tse-Min Chen; Yi-Maun Subeq; Ru-Ping Lee; Tzyy-Wen Chiou; Bang-Gee Hsu
- Book ID
- 108785822
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 590 KB
- Volume
- 89
- Category
- Article
- ISSN
- 0959-9673
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๐ SIMILAR VOLUMES
Acebutolol (AC) is a chiral b-adrenergic blocking drug, possessing intrinsic sympathomimetic activity (ISA), and is useful clinically as the racemate in treating hypertension. Utilizing a stereospeciยฎc high-performance liquid chromatographic (HPLC) assay, the enantiomeric disposition of AC and its m
Acebutolol (AC), is a chiral, i-adrenergic blocking agent which possesses partial agonist activity and is metabolized to an equipotent chiral metabolite, diacetolol (DC). The enantiomeric disposition of AC is reported following racemic administration as a single oral (p.o., 50 mg kg -1 ) or as a mul