Lithium carbonate as a potential pharmacological vehicle: intravenous kinetics of single-dose administration in healthy subjects

Kinetics of acetaminophen after single-

Kinetics of acetaminophen after single- and multiple-dose oral administration as a gradient matrix system to healthy male subjects

✍ Elvira M. G. Van Bomml; Maikel Raghoebar; Josef J. Tukker 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 607 KB

## Abstract The __in vivo__ characteristics of two formulations of a recently developed controlled‐release system, the Gradient Matrix System (GMS‐1 and GMS‐2), with acetaminophen as a model drug compound have been determined in healthy volunteers both after separate single‐ and multiple‐dose admin