๐”– Bobbio Scriptorium
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Single-dose efficacy evaluation of loreclezole in patients with photosensitive epilepsy

โœ Scribed by J. Overweg; F. De Beukelaar


Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
563 KB
Volume
6
Category
Article
ISSN
0920-1211

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๐Ÿ“œ SIMILAR VOLUMES


Efficacy and safety evaluation of lorecl
โœ T Rentmeester; J Hulsman ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 381 KB

Thirteen drug-resistant epilepsy patients received loreclezole as add-on therapy. The trial lasted 6 months. Loreclezole was dosed to reach a target plasma concentration between 1 and 3 mg/l. The seizure frequency in the total group decreased by 23%. A reduction of 50% or more was observed in four p

A double-blind, placebo-controlled evalu
โœ T Rentmeester; A Janssen; J Hulsman; F Scholtes; B van der Kleij; J Overweg; J M ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 655 KB

Sixty-two patients with uncontrolled partial seizures participated in a 12-week, double-blind, placebo-controlled add-on-trial. Thirty-two patients received loreclezole and 30 a placebo as add-on therapy. Loreclezole was targeted at a plasma level of 1-2 mg/l. In spite of an antiepileptic therapy, u

Long-term evaluation of the efficacy and
โœ T. Rentmeester; A. Janssen; J. Hulsman; F. Scholtes; B. van der Kleij; J. Overwe ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 534 KB

The effect and safety of loreclezole were evaluated during a long-term follow-up trial targeting higher plasma concentrations than those of the preceding controlled trial. The result is better than in the double-blind trial, in which loreclezole doses were administered to reach plasma concentrations