Background. RG 12915 is a potent, selective 5-HT3 receptor antagonist with a biologic half-life of 31-20 hours. RG 12915 prevents cisplatin-induced emesis in ferrets at doses of 0.03 mg/kg. Animal toxicology studies permitted safe testing in humans at doses of up to 2.0 mg/kg. This dose-ranging tria
Dose-ranging evaluation of the antiemetic efficacy of intravenous dolasetron in patients receiving chemotherapy with doxorubicin or cyclophosphamide
β Scribed by Paul J. Hesketh; David R. Gandara; Ann M. Hesketh; Anna Facada; Edith A. Perez; Lauri M. Webber; Lorene A. Martin; Michael B. Cramer; William F. Hahne
- Publisher
- Springer-Verlag
- Year
- 1996
- Tongue
- English
- Weight
- 619 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0941-4355
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