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Single-Channel Kinetic Analysis for Activation and Desensitization of Homomeric 5-HT3A Receptors

✍ Scribed by Corradi, Jeremias; Gumilar, Fernanda; Bouzat, Cecilia B.


Book ID
123251093
Publisher
Biophysical Society
Year
2009
Tongue
English
Weight
60 KB
Volume
96
Category
Article
ISSN
0006-3495

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## Abstract The affinity of a ligand for a receptor is usually expressed in terms of the dissociation constant (__K__~__i__~) of the drug‐receptor complex, conveniently measured by the inhibition of radioligand binding. However, a ligand can be an antagonist, a partial agonist, or a full agonist, a