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Conformation-activity relationship study of 5-HT3 receptor antagonists and a definition of a model for this receptor site

✍ Scribed by Hibert, Marcel F.; Hoffmann, Remy; Miller, Robert C.; Carr, Albert A.


Book ID
120310336
Publisher
American Chemical Society
Year
1990
Tongue
English
Weight
874 KB
Volume
33
Category
Article
ISSN
0022-2623

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Zatosetron, a selective 5-HT3 receptor a
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## Abstract Zatosetron is a potent, orally active 5‐HT~3~ receptor antagonist with a long duration of activity in laboratory animals and humans. Several metabolites have been detected in plasma and urine of humans and experimental animals receiving zatosetron. The present study was designed to expl