๐”– Bobbio Scriptorium
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Single central incisor in familial holoprosencephaly

โœ Scribed by Susan A. Berry; Mary Ella Pierpont; Robert J. Gorlin

Book ID
119460857
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
596 KB
Volume
104
Category
Article
ISSN
1097-6833

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A holoprosencephalic child was born to a mother with a single central maxillary incisor. The infant had a median cleft lip, a flat nose with a single nostril, hypotelorism, and normal chromosomes. The head was brachycephalic and small, and computed tomography (CT) of the brain showed semilobar holop

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## Abstract Three patientsโ€”one with alobar holoprosencephaly and two with a holoprosencephalyโ€like phenotypeโ€”are reported with no identifiable mutations. In each case, one parent had a single maxillary central incisor (SMCI). We briefly review the holoprosencephalyโ€like phenotype and present a tabl