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Simultaneous origin of homochirality, the genetic code and its directionality

✍ Scribed by Robert Root-Bernstein

Publisher: John Wiley and Sons
Year: 2007
Tongue: English
Weight: 204 KB
Volume: 29
Category: Article
ISSN: 0265-9247
DOI: 10.1002/bies.20602

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✦ Synopsis

The origin of homochirality in molecules characterizing living systems has remained a mystery since Pasteur's recognition of the problem some 150 years ago.(2-5) Most theories also assume that homochirality emerged in one class of molecules (e.g. ribose) from which it was enriched in other molecules (e.g. amino acids) as well.(2-5)I propose a novel, experimentally testable hypothesis describing a process by which selective chirality in amino acids and ribonucleotides emerged simultaneously and hand-in-hand with the origin and directionality of the genetic code within a system of interactions involving amino acids, peptides, nucleotide bases, their sugars and polynucleotides.

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