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Simultaneous expression of COX-2 and mPGES-1 in mouse gastrointestinal hamartomas

✍ Scribed by Takeda, H; Miyoshi, H; Tamai, Y; Oshima, M; Taketo, M M

Book ID: 109997935
Publisher: Nature Publishing Group
Year: 2004
Tongue: English
Weight: 193 KB
Volume: 90
Category: Article
ISSN: 0007-0920
DOI: 10.1038/sj.bjc.6601584

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## Abstract Prostaglandin E~2~ (PGE~2~) is among the most important mediators involved in neuroinflammatory processes. The final step of its synthesis is regulated by enzymes termed prostaglandin E~2~ synthases (PGES). Three PGES are known, cytosolic (c)PGES, membrane‐associated (m)PGES‐1 and mPGES