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Simultaneous enantioseparation and sensitive detection of eight β-blockers using capillary electrochromatography-electrospray ionization-mass spectrometry

✍ Scribed by Jack Zheng; Shahab A. Shamsi


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
768 KB
Volume
27
Category
Article
ISSN
0173-0835

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In vitro permeability of eight β-blocker
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It is demonstrated that the apparent permeability coefficients of b-adrenoceptor antagonist drugs can easily (P app ) be determined for Caco-2 cell culture intestinal models utilizing liquid chromatography/mass spectrometry (LC/MS). The LC/MS method with electrospray ionization in the single ion mon